Monitoring procedures in primary progressive multiple sclerosis (PPMS): Cognitive parameters in routine clinical practice

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00023067

Enrollment

Registered

2021-01-12

Start date

2021-03-11

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Progressive Multiple Sclerosis (PPMS)

Interventions

Group 1: N=33 patients participate in a cognitive assessment (memory and attention tests) three times, i.e. upon study inclusion and after 6 and 12 months. There is no treatment involved, only cogniti

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: - verified PPMS Diagnosis according to McDonald criteria (2010) - age between 18 and 75 years

Exclusion criteria

Exclusion criteria: - current major depressive disorder, dysthymic disorder, presence of substance abuse - presence or history of bipolar disorder, borderline personality disorder, schizophrenia or schizoaffective disorder, epilepsy

Design outcomes

Primary

Measure	Time frame
Specification of the subtests of an extensive neuropsychological test battery with highest test-retest reliability. To this end, test-retest reliability is estimated for each cognitive test across three measurement occasions (Time 0: upon inclusion, T1: after 6 months and T2: after 12 months)	—

Secondary

Measure	Time frame
Specification of the subtests of an extensive neuropsychological test battery with highest sensitivity and specificity for overall cognitive performance	—

Countries

Germany

Contacts

Public ContactPatrick Oschmann

Klinik für Neurologie

patrick.oschmann@klinikum-bayreuth.de0921400753440

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026