G20
Conditions
Interventions
Group 1: Healthy elderly will perform motor execution and motor imagery tasks
In four training sessions participants will perform a motor imagery neurofeedback task in order to learn self-regulating their brain activity
primary outcome is to compare the measured fNIRS data from healthy elderly with fNIRS data from Parkinson's disease patients. Further comparisons are planned with arm 2 (healthy elderly participants w
will perform motor execution and motor imagery tasks
In four training sessions participants will perform a motor imagery task in order to learn self-regulating their brain activity (without neurofeedback)
primary outcome is to compare the measured fNIRS data with fNIRS data of the group of elderly subjects receiving neurofeedback (arm 1).
Group 3: Parkinson's Patients
In four training sessions patients will perform a motor imagery neurofeedback task in order to learn self-regulating their brain activity
primary outcome is to compare the measured fNIRS data of the patients with fNIRS data from the healthy elderly participants group (arm 1).
Sponsors
Neurokognition und Funktionelle Neurorehabilitation Abteilung für Neuropsychologie Department für Psychologie Carl von Ossietzky Universität Oldenburg
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: Diagnosis of Parkinson's Disease according to UK PD Society Brain Bank Criteria (Hughes et al., 1992) within a Hoehn & Yahr stadium of 1 –3
Exclusion criteria
Exclusion criteria: All: - any affection of the central nervous system - psychological and psychiatric diseases - cognitive impairment as measured by the MoCa (Cut-off of 25 points) - less than 4 hours of sleep Parkinson's Patients: - stable medication all along the study duration - Dementia at a PANDA cut-off value of 18 points (Kalbe et al., 2008)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome is to measure with fNIRS the increase/decrease of oxygenated/deoxygenated hemoglobin concentration changes of the SMA over the four training sessions. It is expected that the SMA activity is increased post-training as compared to pre-training measurements. The concentration changes of healthy elderly subjects and of the Parkinson's disease patients will be compared. Furthermore, a comparison of healthy elderly participants receiving neurofeedback and the group of healthy elderly subjects not receiving neurofeedback will be conducted. | — |
Secondary
| Measure | Time frame |
|---|---|
| As a secondary measure the electromyogram (EMG) of the upper limbs will be measured. It will be investigated whether the EMG changes over the training sessions and afterwards; furthermore, it will be explored whether these changes differ between the patient group and the groups of healthy elderly participants (with and without neurofeedback). | — |
Countries
Germany
Contacts
Public ContactCornelia Kranczioch
Neurokognition und Funktionelle Neurorehabilitation Abteilung für Neuropsychologie Department für Psychologie Carl von Ossietzky Universität Oldenburg
Outcome results
None listed