G62.0
Conditions
Interventions
Group 1: Needle acupuncture 1x / week of 20 minutes for 16 weeks
Group 2: Vibration training twice a week for 16 weeks
Group 3: Needle acupuncture waiting list
Sponsors
Hamburger Krebsgesellschaft e.V.
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Chemotherapy with a treatment regimen containing oxaliplatin of at least 3 months duration (cumulative dose of oxaliplatin> 500 mg / m2) regardless of the intention (adjuvant or palliative) Minimum age 18 years
Exclusion criteria
Exclusion criteria: Polyneuropathy of other origins (diabetes mellitus, alcohol abuse, paraneoplastic, consequences of previous chemotherapy, hereditary, chronic inflammatory, idiopathic etc.) Illnesses jeopardize patient safety or the feasibility of the study, e.g. Coagulopathy or use of anticoagulants with a bleeding time> 3 min, prothrombin time 50 sec Bacterial infection on the upper or lower extremities near the site of the planned acupuncture therapy Bone fracture of the upper or lower extremities in the past 3 months Osteolysis o osteosynthesis, knee or hip replacement Acute thrombosis Alcohol addiction Or other diseases that the investigator believes jeopardize the safety of the patient or the feasibility of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delta of the amplitude of the sensory nerve action potential of the sural nerve after 4 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitive nerve conduction velocity of the sural nerve (N.Suralis SNLG) Clinical neurological parameters: Sensitive qualities, temperature, pallesthesia, 2-point discrimination, gait tests, pain. Neuropathy Deficit Score (NDS) (Dyck 1992) Neuropathy Symptom Score (NSS) (Dyck 1992) Numerical Rating Scale (NRS) (Farrar 2001) Depth sensitivity (tuning fork test) Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) Coordinative performance (Center of PressureMessung, Short Physical Performance Battery SPPB) Strength ability (strength test, isometric using a hand strength dynamometer). Parameters are taken on inclusion examination, after 4 month and after 12 month | — |
Countries
Germany
Contacts
Public ContactSven Schröder
TCM am UKE
Outcome results
None listed