Complex regional pain syndrome and primary headache: case of coincidence or causality?

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00022961

Enrollment

200

Registered

2021-03-25

Start date

2021-03-23

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complex regional pain - syndrom G90.50

Interventions

Group 1: Patients with CRPS are interviewed once with a questionnaire on concomitant diseases, disease severity and quality of life

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Diagnosis of CRPS

Exclusion criteria

Exclusion criteria: non

Design outcomes

Secondary

Measure	Time frame
Anamnestic improvement not only of headache but also of neuropathic pain in patients after starting a CGRP antibody therapy (H2) Positive association between the occurrence of fatigue and severity of the CRPS disease (H3 CRPS alone; H4: CRPS+migraine).	—

Primary

Measure	Time frame
The primary outcome criterion is the prevalence of primary headache, especially trigeminal autonomic headache with CRPS	—

Countries

Germany

Contacts

Public ContactSebastian Strauss

Klinik und Poliklinik für Neurologie

Sebastian.Strauss@med.uni-greifswald.de03834 86-6815

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026