I64
Conditions
Interventions
Group 1: Stroke survivors (sub-acute)
The patients will be assessed at inclusion using the robotic, as well as the clinical and neurophysiological assessments. After two weeks, they will be assessed
Sponsors
Kliniken Schmieder Allensbach
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Diagnosis of stroke (ischemic or hemorrhagic) 2. Subacute stroke at study inclusion (< 3 months since stroke at first measurement) 3. Sufficient cognitive function to understand task instructions (as assessed by the recruiting physiotherapist) 4. No pain when inserting the index finger in the robotic device 5. Minimum passive range of motion of the index finger (30 degrees) 6. No strong spasticity (Modified Ashworth Scale <= 3) 7. At least 40% of recruited subjects (20/50) should have some proprioceptive deficits according to the clinical scale (kinaesthetic Up-Down test from NSA < 3) 8. At most 40% of recruited subjects (20/50) should stay in the clinic < 5 weeks (inclusion and discharge measurement only)
Exclusion criteria
Exclusion criteria: For TMS only: 1. Heart pacemaker 2. Metallic implants in the brain 3. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Robotic metrics. What and how: e.g. index finger velocity, position, force - metrics extracted from the robotic device ETH MIKE (as described here: https://ieeexplore.ieee.org/document/8779507) When: at every measurement point (every 2 weeks while patients are undergoing usual rehabilitation) | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical outcomes: Box & Block test, Nottingham Sensory Assessment, Montreal Cognitive Assessment, Fugl-Meyer Assessment, Barthel Index, Neglect Assessment (Bell Test); Neurophysiology: MEP and SSEP amplitude & latency; Neuroimaging: lesion location These are only collected at inclusion and after 4 weeks of rehabilitation. | — |
Countries
Germany
Contacts
Public ContactMonika Zbytniewska
ETH Zürich
Outcome results
None listed