T84.5 T84.0 T84.8
Conditions
Interventions
Group 1: Joint tap and aspiration of synovial fluid
Group 2: Punch biopsy of a prostetic joint and extraction of 5-7 biopsies from the synovial membrane
Sponsors
Department für Bewegungschirurgie - Vivantes Humboldt-Klinikum
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Preceding implantation of a shoulder, hip or knee endoprosthesis - Acute or chronic pain in the joint - Periprosthetic fracture - Instability of the endoprosthesis - Indications of wear / insufficiency of the enclosed plastic spacers - Indications of metal abrasion - Primary misalignment of the implant
Exclusion criteria
Exclusion criteria: - Confirmed periprosthetic infection - Proven allergy to fast-acting local anesthetics
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the respective examination results of the punch biopsies, the synovial fluid, pre-interventional blood analysis and the samples taken during the endoprosthesis replacement operation, in particular the sonicate of the prosthesis and the periprosthetic membrane (gold standard for infection diagnostics) | — |
Secondary
| Measure | Time frame |
|---|---|
| Analysis and comparison of the results of pathomorphological examinations of the punch biopsies and the samples taken during the replacement operation with regard to wear particles | — |
Countries
Germany
Contacts
Public ContactRafal Jerzy Borucki
Klinik für Endoprothetik, Unfallchirurgie und Orthopädie, Vivantes Humboldt Klinikum
Outcome results
None listed