Impact of the untargeted use of rapid high-sensitivity Aspergillus assays on diagnosis rate and time to detection of invasive pulmonary aspergillosis in intensive care units

Impact of the untargeted use of rapid high-sensitivity Aspergillus assays on diagnosis rate and time to detection of invasive pulmonary aspergillosis in intensive care units - RADICAL (Rapid Diagnosis of ICU Aspergillosis)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00022920

Enrollment

650

Registered

2020-08-24

Start date

2020-10-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

B44.0

Interventions

Group 1: The following examinations are carried out as soon as a BAL for infection diagnostics is received by the microbiological institute: - Routine microbiological diagnostics with microscopy and c

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Receipt of a BALF in the microbiology lab

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
WHAT: Number of "proven" and "probable" invasive pulmonary aspergillosis cases WHEN: after testing of the BAL samples HOW: Classification according to EORTC / MSG criteria into "proven", "probable", "possible" and "unlikely" invasive pulmonary aspergillosis	—

Secondary

Measure	Time frame
Sensitivity and Specificity of the Aspergillus Assays Time to detect Aspergillus	—

Countries

Germany

Contacts

Public ContactJürgen Held

Mikrobiologisches InstitutUniklinik Erlangen

juergen.held@uk-erlangen.de091318546903

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026