Sex differences in rehabilitating Parkinson's Disease - Modulating effects of standardised rehabilitation programs on motor and non-motor symptoms -

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

DRKS

Registry ID

DRKS00022773

Enrollment

Registered

2020-08-18

Start date

2020-08-05

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G20

Interventions

Group 1: There will be one intervention group, divided into two subgroups (male/female) without a control. All participants are patients in local, neurologic rehabilitation clinics, receiving a certif

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - participants of staionary treatment - diagnosed with ICD-number: G20.-

Exclusion criteria

Exclusion criteria: - known allergies or hypersensitivity against the materials of the wrist bands: silicon, polycarbonate, gold, glass fiber, thermoplastic, polyurethane, silver, silicon glue, light - known allergies or hypersensitivities against materials of the chest strap: polyamide, polyurethane, elastane, polyester, silicon - dermatosis or skin lesion in the areas of sensor application (wrist, torso) - known sex chromosome aberrations - no definite biologic sex category - pregnancy or lactation period - concurrent participation in further studies, that require additional theraphy / intervention

Design outcomes

Primary

Measure	Time frame
a)Sex-specific differences (before versus after treatment) of motor symptoms -Activities of daily living (DeMorton Mobility Index) -Independent walking (Functional Ambulation Categories) -Walking speed (10m-Gehtest) b)Sex-specific differences (before versus after treatment) of subjectively perceived symptoms -Sleep disorders (PDSS-2) -Autonomic dysfunction (SCOPA-AUT) c)Sex-specific differences (before versus after treatment) of cardiovascular Symptoms -Heart rate in supine rest and during adaption to supine rest -Blood pressure during supine rest, during orthostasis and during adaption to supine rest c)Sex-specific differences (before versus after treatment) in parameters of autonomic control -RMSSD during supine rest and adaption to supine rest (parasympathetic) -meanEDA during supine rest and adaption to supine rest (sympathetic)	—

Measure

Time frame

a)Sex-specific differences (before versus after treatment) of motor symptoms -Activities of daily living (DeMorton Mobility Index) -Independent walking (Functional Ambulation Categories) -Walking speed (10m-Gehtest) b)Sex-specific differences (before versus after treatment) of subjectively perceived symptoms -Sleep disorders (PDSS-2) -Autonomic dysfunction (SCOPA-AUT) c)Sex-specific differences (before versus after treatment) of cardiovascular Symptoms -Heart rate in supine rest and during adaption to supine rest -Blood pressure during supine rest, during orthostasis and during adaption to supine rest c)Sex-specific differences (before versus after treatment) in parameters of autonomic control -RMSSD during supine rest and adaption to supine rest (parasympathetic) -meanEDA during supine rest and adaption to supine rest (sympathetic)

—

Secondary

Measure	Time frame
Correlations of outcomes with: age, BMI, duration of Parkinson disease, cardiovascular diseases, anti-hypertensive medication	—

Countries

Germany

Contacts

Public ContactFranziska Siche-Pantel

Sportmedizinisches Institut der Universität Paderborn

siche-pantel@sportmed.upb.de05251 60 3586

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026