A prospective clinical study on antibiotic therapy and effects on local odontogenic abscesses

A prospective clinical study on antibiotic therapy and effects on local odontogenic abscesses - n.a

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

DRKS

Registry ID

DRKS00022482

Enrollment

Registered

2020-07-29

Start date

2018-10-30

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K04.7 A01

Interventions

Group 1: Patients in this group receive antibiosis after surgical abscess opening. Penicillin (Amoxiclavulan 875/125mg, 1-0-1) for allergy (Clindamycin 600mg 1-0-1) for a total of 7 days. Group 2: Pat

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Exclusively odontogenic abscesses Clinical signs of inflammation of an abscess adult and healthy patients of both sexes with dentogenic abscess

Exclusion criteria

Exclusion criteria: General illnesses for which an antibiosis is indicated (endocarditis, immunosuppression, HIV infection, diabetes mellitus, radiation, chemotherapy, antiresorptive medication Abscesses with a tendency to spread (trismus, difficulty in swallowing, difficulty in breathing,V.angularis pressure dolence) Patients who, due to the medical indication, must formally change from group 2 to 1 within the study period

Design outcomes

Primary

Measure	Time frame
The improvement of the blood values CRP/leukocytes/fever measurement in group comparison Start of the endpoint upon inclusion in the study collective.	—

Secondary

Measure	Time frame
The improvement of the subjective parameters VAS in group comparison	—

Countries

Germany

Contacts

Public ContactMayte Buchbender

Mund-Kiefer- und Gesichtschirurgie FAU Erlangen

mayte.buchbender@uk-erlangen.de091318533614

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026