Physiological Effects of Auditory Stimulation on Patients after Aneurysmal Subarachnoid Hemorrhage - Influence of Classical Music in aneurysmal Subarachnoid Hemorrhage

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00022431

Enrollment

Registered

2020-07-09

Start date

2020-07-10

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I60.0

Interventions

Group 1: All patients receive auditory stimulation with classical music from W.A. Mozart, Symphony No. 40, G minor, KV 550. Physiological parameters such as heart rate, blood pressure, etc. as well as

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Evidence of aneurysmal subarachnoid hemorrhage using computed tomography (CT), magnetic resonance imaging (MRI) or lumbar puncture and an imaging method to detect the aneurysm, i.e. digital subtraction angiography (DSA), CT or MRI angiography 2) Secure of the aneurysm using endovascular or microsurgical procedures 3) Written informed consent to the study or written informed consent from an authorized representative

Exclusion criteria

Exclusion criteria: 1) Existing surgical wounds or drainage that are incompatible with the headphone or TCD probe 2) Hypacusis or anacusis 3) pregnancy of the patient 4) Participation in an intervention study within the past 30 days 5) Any other reasons that preclude study participation from the study director's perspective

Design outcomes

Primary

Measure	Time frame
Change in the cerebral flow velocities of the blood in the cerebral artery using TCD with continuous ICP measurement while playing classical music in patients with aneurysmal subarachnoid hemorrhage.	—

Secondary

Measure	Time frame
1) Change of physiological parameters, in example blood pressure, heart rate, respiratory rate, oxygen saturation, intracranial pressure (if measured), in patients with aneurysmal subarachnoid hemorrhage 2) Effect of classical music on the rate of Delayed Cerebral Ischemia (DCI) 3) Influence of existing analgesia on the primary endpoint or secondary endpoints 1 and 2. 4) Effect of classical music on the neurological outcome upon discharge, determined after 3 or 6 months by the Extended Glasgow Outcome Scale 5) Effects of classical music on selected psychological parameters, measured using the Hospital Anxiety and Depression Scale method - German version (Snaith & Zigmond, 2010)	—

Measure

Time frame

1) Change of physiological parameters, in example blood pressure, heart rate, respiratory rate, oxygen saturation, intracranial pressure (if measured), in patients with aneurysmal subarachnoid hemorrhage 2) Effect of classical music on the rate of Delayed Cerebral Ischemia (DCI) 3) Influence of existing analgesia on the primary endpoint or secondary endpoints 1 and 2. 4) Effect of classical music on the neurological outcome upon discharge, determined after 3 or 6 months by the Extended Glasgow Outcome Scale 5) Effects of classical music on selected psychological parameters, measured using the Hospital Anxiety and Depression Scale method - German version (Snaith & Zigmond, 2010)

—

Countries

Germany

Contacts

Public ContactPatrick Czorlich

Universitätsklinikum Hamburg-EppendorfKlinik und Poliklinik für Neurochirurgie

p.czorlich@uke.de0049-40-7410-53750

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026