DSM-V: F32.1 - F32.2
Conditions
Interventions
Group 1: Moderate to vigorous physical activity (MVPA) - 30 minutes continous method
10 minutes warm-up, 5 minutes cool-down
randomized order of exercise in a within-subject-design
Group 2: Aerobic interval training (AIT) - 4 high intensity intervals (each 4 minutes) and 4 active breaks (each 5 minutes)
randomized order of exercise in a within-subject-design
Group 3: inactive control - 30 minutes sitting
randomized order of exercise in a within-subject-design
Sponsors
Eberhard Karls Universität Tübingen
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: informed, written consent; currently diagnosed moderate depression diagnosed with SKID-V (F32.1-F32.1, F33.1-F33.2); BDI-II Score > 20; Age between 18-40 years; fluent german skills; no psychopharmacological treatment; waiting period for ambulant psychotherapy > 2 months
Exclusion criteria
Exclusion criteria: acute suicidality; schizophrenia and other psychotic disorders (F23, F20.81, F20.9 DSM-V); acute substance misuse except for tabacco (F10, F11, F12, F13, F14, F15, F16, F18, F19 DSM-V); current psychotherapy or start during the study period; current psychopharmacological treatment or start during study period; regular exercise (more then once a week for 30 minutes at a time endurance orientated exercise; e.g. jogging, cycling, swimming); acute or chronic diseases influencing brain metabolism: diabetes mellitus (E10-E14 ICD-10), kidney insufficiency from stadium 3 of the kidney disease outcome quality initative, non-adjusted hypertension (I10.x ICD-10), moderate to severe craniocerebral trauma (GSC 3-12) or rather craniocerebral trauma second or third degree with loss of concouisness for more than 30 minutes; medical contraindications for exercise: acute infectious diseases, medication intake, which in the opinion of the study physician do not permit an inclusion, allergic diseases in an acute episode, severe metabolic diseases, non-adjusted hypertension, cardiovascular diseases, orthopedic symptoms, which in the opinion of the study physician do not permit an inclusion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decoders, which have been trained for each subject individually, are used to decode neurophysiological data (EEG, fNIRS) during exercise. It is then compared how often rumination, distraction and positive mood are decoded during active conditions (MVPA, AIT) compared to the inactive control condition. Furthermore, it is considered how decoded severity of rumination differs between the three conditions. | — |
Secondary
| Measure | Time frame |
|---|---|
| Additionally to the decoders subjective data should be included. Therfore questionnaires concerning rumination and affect are executed before and after exercise (Perservative Thinking Questionnaire - State; Positive and Negative Affect Schedule). It is considered to what extent the questionnaires concerning rumination and affect differ in the active conditions (MVPA, AIT) compared to the inactive control condition. | — |
Countries
Germany
Contacts
Public ContactJana Welkerling
Eberhard Karls Universität Tübingen
Outcome results
None listed