K02
Conditions
Interventions
Proctor & Gamble, Schwalbach am Taunus, Ger
Schirrmeister et al., 2007]. Each specimen included one sound enamel/dentin area and one demineralized lesion.
The factors under evaluation will be:
• ‘intervention’ at four levels: daily tooth brushi
Sponsors
Universität BernKlinik für Zahnerhaltung, Präventiv- und Kinderzahnmedizin
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • give written informed consent; • be between the ages of 18 and 70; • be in good general health; • agree not to participate in any other clinical study for the duration of this study; • agree to refrain from using any non-study oral hygiene products including: toothbrushes, dentifrices, mouth rinses, tooth whitening products or floss for the study duration other than their usual toothbrush and toothpaste which will be used during the Acclimation period between each visit; • have a minimum of 20 teeth (excluding third molars); • agree to return for the scheduled clinical visits and follow study procedures
Exclusion criteria
Exclusion criteria: • active participation in another oral/dental products clinical study; • current severe chronic illness or infectious disease; • drug or alcohol abuse; • eating disorders, • pregnancy or breast feeding; • antibiotic use (2 months before and during study) or medication reducing salivary flow; • intake of other medications that might have an impact on the outcome; • bad oral cleanliness, no agreement to comply with study design; • known allergic reactions to any of the test substances; • other allergic reactions to dental materials or oral hygiene products
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| At the participant level, the primary endpoint is reached after 20 weeks (final examination and delivery of the fourth phase appliance, nutritional protocol, products and toothbrush). At the specimen level, the primary endpoint is reached after the evaluation of the mineral content and the lesion depth of the specmines and after evaluation of the biofilm on the samples. | — |
Countries
Switzerland
Contacts
Public ContactRichard Wierichs
Universität BernKlinik für Zahnerhaltung, Präventiv- und Kinderzahnmedizin
Outcome results
None listed