Normative values for contact heat- and cold-evoked potentials

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00022299

Enrollment

200

Registered

2020-11-05

Start date

2020-11-12

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers

Interventions

Group 1: On visit 1, patients who meet the inclusion criteria (healthy, age 18+, no language barriers) and give their informed written consent to participate are examined neurologically with a focus o

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Healthy subjects, aged 18- 80+

Exclusion criteria

Exclusion criteria: Subjects with internal, neurological or psychiatric diseases affecting the peripheral or central nervous system and subjects on regular medication are excluded. Further exclusion criteria: pregnancy, insufficient skills in German language

Design outcomes

Primary

Measure	Time frame
Establishing normative values for CHEPs and CEPs assessed with TCS II is the primariy outcome of this study. Contact- heat and cold stimuli are applied with the TCS II on the face, hand dorsum, thorax and foot dorsum. The evoked potentials are recorded with EEG. This is conducted in visit 2.	—

Secondary

Measure	Time frame
assessment of CHEPs habituation and SSR on visit 1	—

Countries

Germany, Switzerland

Contacts

Public ContactDilara Kersebaum

Universitätsklinikum Schleswig- Holstein Campus KielKlinik für NeurologieSektion Neurologische Schmerzforschung und -therapie

dilara.kersebaum@uksh.de043150023911

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026