G20.11
Conditions
Interventions
Group 1: Patients with deep brain stimulation are examined in a "cross over design" on 2 examination dates. At one appointment, the deep brain stimulation will remain switched on. Then the motor learn
Sponsors
Klinik für Neurologie, Uniklinik Leipzig
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: - Persons aged 30 to 75 years; - Specific to persons with Parkinson's disease: condition following implantation of a system for deep brain stimulation of the subthalamic nucleus and current therapy - Specific for people with Parkinson's disease: Hoehn and Yahr stages 1 to 4 - Right handed - Signing of the declaration of consent
Exclusion criteria
Exclusion criteria: - Non-consent or inability of the subject to consent to participate in the study - Alcohol/drug abuse (current or previous history) - other neurological diseases with the exception of idiopathic Parkinson's syndrome - Depression (BDI > 19 points) - acute psychotic symptoms - serious pre-existing medical conditions (e.g. heart failure) or pre-existing orthopaedic/rheumatological conditions that interfere with the execution of the expenditure - inability to perform the experimental tasks - Pregnancy according to self-disclosure - relevant cognitive impairment (MOCA score 12)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ability of motor learning or the consolidation of what has been learned in THS mode on or off | — |
Secondary
| Measure | Time frame |
|---|---|
| Influence of the stimulation site of THS in the STN on motor learning or consolidation | — |
Countries
Germany
Contacts
Public ContactJost-Julian Rumpf
Klinik für Neurologie, Uniklinik Leipzig
Outcome results
None listed