Multicenter randomized controlled clinical trial comparing immediate to delayed loading in dental implant treatment applying a full-digital workflow

Multicenter randomized controlled clinical trial comparing immediate to delayed loading in dental implant treatment applying a full-digital workflow - IL vs DL

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00022286

Enrollment

Registered

2022-01-20

Start date

2022-01-31

Completion date

Unknown

Last updated

2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K00-K14

Interventions

Group 1: Immediate implant loading, within 3-7 days after implant placement Group 2: Delayed implant loading, after 3 months of implant placement

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - In need of at least two or more unilateral implants at the posterior region either in the maxilla or the mandible (excl. third molars) (single crowns only) - Primary implant stability with insertion torque > 30N - Presence of two adjacent teeth at the implant site - Adequate oral hygiene (Bleeding on probing <20%; Plaque index <20%); - Capability to comply with the study procedures - Signed Informed Consent Form

Exclusion criteria

Exclusion criteria: - Pregnant or lactating women - Systemic or local conditions presenting a contraindication to implant treatment - Known or suspected non-compliance, drug or alcohol abuse - Smokers (>10 cigarettes/day) - Currently taking drugs that influence bone metabolism - Use of bisphosphonates in the last 4 years - History of malignancy, radiotherapy or chemotherapy for malignancy in the past 5 years

Design outcomes

Primary

Measure	Time frame
Patients’ satisfaction using Patient Reported Outcome Measures (PROMs) (VAS), after 12 months.	—

Secondary

Measure	Time frame
- Perceived difficulty/ease of use rated by dentists evaluated (VAS) - Patient’s reported outcome measures (patient’s expectations, and OHIP-14 - Efficiency (time) - Marginal bone level (implant shoulder to first bone-to-implant-contact) after insertion of the final reconstruction, 6 months and 1-year follow-up - Implant survival at 6 months and 1-year follow-up - Schedule of visits plus and additional visits (efficiency) - Treatment cost - Peri-implant clinical parameters ( PD,PI, BOP, REC,KER, at the implant sites after insertion of the final reconstruction, at 6 months and at 1-year follow-up - Implant-supported crown height after insertion of the final reconstruction, at 6 months and 1-year follow-up - Accuracy of implant position - Fit of final reconstruction after its insertion - Technical outcomes (efficacy/USPHS) after insertion of the final reconstruction, and at 1-year follow-up	—

Measure

Time frame

- Perceived difficulty/ease of use rated by dentists evaluated (VAS) - Patient’s reported outcome measures (patient’s expectations, and OHIP-14 - Efficiency (time) - Marginal bone level (implant shoulder to first bone-to-implant-contact) after insertion of the final reconstruction, 6 months and 1-year follow-up - Implant survival at 6 months and 1-year follow-up - Schedule of visits plus and additional visits (efficiency) - Treatment cost - Peri-implant clinical parameters ( PD,PI, BOP, REC,KER, at the implant sites after insertion of the final reconstruction, at 6 months and at 1-year follow-up - Implant-supported crown height after insertion of the final reconstruction, at 6 months and 1-year follow-up - Accuracy of implant position - Fit of final reconstruction after its insertion - Technical outcomes (efficacy/USPHS) after insertion of the final reconstruction, and at 1-year follow-up

—

Countries

South Korea, Switzerland

Contacts

Public ContactRoland E. Jung

University of ZürichCenter of Dental MedicineClinic of Reconstructive Dentistry

roland.jung@zzm.uzh.ch+41 44 63433 11

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026