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Investigation of microcirculation via LASCA in patients with CRPS

Investigation of microcirculation via LASCA in patients with CRPS

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00022256
Enrollment
80
Registered
2020-07-24
Start date
2018-04-24
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CRPS of the upper extremity (G90.50, G90.60, G90.70) M79.64

Interventions

Group 1: patients with CRPS (Complex Regional Pain Syndrome) (single visit: fLASCA while warming the skin of both hands, QST, questionnaires about pain, quality of life and psychological factors) Grou

Sponsors

Sektion Neurologische Schmerzforschung und -therapieUniversitätsklinikum Schleswig-Holstein, Campus Kiel
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 90 Years

Inclusion criteria

Inclusion criteria: - proven diagnosis of CRPS - affected controls: unilateral pain disorders of the hand existing for at least 3 months (ganglion, carpal tunnel syndrome, arthrosis, rheumatic diseases, Dupuytren, s/p fracture) without signs of CRPS, age- and gendermatched to CRPS patients - healthy subjects: healthy volunteers, age- and gendermatched to CRPS patients

Exclusion criteria

Exclusion criteria: - not being able to lie still - nicotine or caffeine consumption less than 8 hours ago - medication, which may influence the measurements healthy controls: - intake of analgesics in the last 14 days - current pain - current severe medical conditions - migraines - medication, which may influence the measurements - alcohol or drug abuse - pathological achilles tendon reflex - palhypaesthesia of the malleolus medialis - pathological QST - positive screening for depression or anxiety (HADS)

Design outcomes

Primary

MeasureTime frame
This study aims to investigate the microcirculation of the skin and compare it to healthy controls and patients with other unilateral pain disorders of the hand existing for at least 3 months.

Secondary

MeasureTime frame
- differences regading sensory profiles (QST) - differences regarding quality of life, mental health and different aspects of pain - differences between healthy and affected hand - The secondary endpoint is assessed parallel to the primary endpoint.

Countries

Germany

Contacts

Public ContactAntonia Sziegoleit

Sektion Neurologische Schmerzforschung und -therapieUniversitätsklinikum Schleswig-Holstein, Campus Kiel

antonia.sziegoleit@uksh.de043150023911

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026