CRPS of the upper extremity (G90.50, G90.60, G90.70) M79.64
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - proven diagnosis of CRPS - affected controls: unilateral pain disorders of the hand existing for at least 3 months (ganglion, carpal tunnel syndrome, arthrosis, rheumatic diseases, Dupuytren, s/p fracture) without signs of CRPS, age- and gendermatched to CRPS patients - healthy subjects: healthy volunteers, age- and gendermatched to CRPS patients
Exclusion criteria
Exclusion criteria: - not being able to lie still - nicotine or caffeine consumption less than 8 hours ago - medication, which may influence the measurements healthy controls: - intake of analgesics in the last 14 days - current pain - current severe medical conditions - migraines - medication, which may influence the measurements - alcohol or drug abuse - pathological achilles tendon reflex - palhypaesthesia of the malleolus medialis - pathological QST - positive screening for depression or anxiety (HADS)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| This study aims to investigate the microcirculation of the skin and compare it to healthy controls and patients with other unilateral pain disorders of the hand existing for at least 3 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| - differences regading sensory profiles (QST) - differences regarding quality of life, mental health and different aspects of pain - differences between healthy and affected hand - The secondary endpoint is assessed parallel to the primary endpoint. | — |
Countries
Germany
Contacts
Sektion Neurologische Schmerzforschung und -therapieUniversitätsklinikum Schleswig-Holstein, Campus Kiel