Healthy volunteers
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Written declaration of consent to participate - Ages 18-65 years - Weight 50-120kg
Exclusion criteria
Exclusion criteria: - Under 18 years - Over 65 years old - Under 50kg - Over 120kg - Injuries or limitations of the lower extremities - Cardiological diseases or taking the following medications: 1. Blood pressure medication of any kind (b-blockers, calcium channel blockers, ACE inhibitors, diuretics, sartans, renin inhibitors) 2. Heart failure medication (aldosterone antagonists, ARNI, cardiac glycosides) 3. Blood thinners (Marcumar, factor Xa inhibitors, ASA) - Respiratory diseases or taking the following medications: 1. Stimulants such as ß2 sympathomimetics 2. Inhaled corticoids - Acute infections - condition after Thrombosis or pulmonary embolism - Muscle disorders - Neurological diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The aim of this investigation is the measurement of various physiological parameters on a treadmill with weight reduction through positive pressure on the lower body in the anti-gravity treadmill system AlterG (AlterG INC., 48438 Milmont Drive, Fremont, CA 94538, Tel .: 510-270-5900 , www.alter-g.com) in healthy subjects. | — |
Secondary
| Measure | Time frame |
|---|---|
| The AlterG treadmill uses a lower body inflation chamber in which excess pressure is generated to reduce the weight of the runner. Weight reduction can have a relieving effect on the cardiovascular system and local muscle activation. For this purpose, the parameters heart rate and blood pressure (systolic / diastolic), VO2, VCO2, AMV and AF should be determined via spirometry depending on different running speeds at 100% body weight and compared with the same running speeds but different body weight reduction on the AlterG. | — |
Countries
Germany
Contacts
BG Klinikum Hamburg