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Assessment of tissue perfusion of pancreatic cancer by means of Intravoxel incoherent motion MRI and CT perfusion: Correlation with histological microvessel density as ground truth.

Assessment of tissue perfusion of pancreatic cancer by means of Intravoxel incoherent motion MRI and CT perfusion: Correlation with histological microvessel density as ground truth. - Pancreatic Cancer-Perfusion

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00022227
Enrollment
23
Registered
2020-06-26
Start date
2014-08-18
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C25

Interventions

Group 1: No randomization. Single-arm trial. In every study participant, the following radiological examinations are conducted on the day before planned surgery in curative intent: 1) Intravoxel incoh

Sponsors

Diagnostische und Interventionelle Radiologie Universitätsklinikum Heidelberg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1) Presence of a mass suspicious of pancreatic cancer in a previous CT and/or MRI. 2) Scheduled surgery with planned resection of the mass.

Exclusion criteria

Exclusion criteria: 1) General contraindications for the application of iodinated contrast agents. 2) MR-unsafe foreign bodies. 3) Previous treatment for pancreatic carcinoma. 4) inability to reproduce the breathing technique.

Design outcomes

Primary

MeasureTime frame
Correlation of perfusion measurements by a) IVIM DW MRI and b) CT-perfusion.

Secondary

MeasureTime frame
Correlation of a) perfusion measurements by imaging (IVIM DW MRI and CT perfusion) and b) histopathological microvessel density.

Countries

Germany

Contacts

Public ContactPhilipp Mayer

Diagnostische und Interventionelle Radiologie Universitätsklinikum Heidelberg

philipp.mayer@med.uni-heidelberg.de004962215637345

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 24, 2026