M81.9 M85.9
Conditions
Interventions
Group 1: DXA (dual x-ray absorptiometry), HRpQCT (high-resolution, quantitative, peripheral computer tomography) and CortBS in subjects with DXA aBMD T-Score <-2.5 (osteoporotic)
Group 2: DXA, HRpQCT
Sponsors
Charité Campus Benjamin Franklin
Eligibility
Sex/Gender
Female
Age
55 Years to No maximum
Inclusion criteria
Inclusion criteria: (i) women >55 years of age; (ii) written informed consent to participate in the study (patient consent); (iii) DXA BMD proximal femur or lumbar spine T-score < -1.0
Exclusion criteria
Exclusion criteria: (i) BMI > 30; (ii) oedema, metal implants or paralysis of the lower limb to be measured; (iii) participants who are unable to undergo the examinations required by the protocol or who have cognitive limitations that preclude understanding the study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The correlations of the cortical pore size with the numerically and experimentally derived backscatter parameters are comparable. | — |
Secondary
| Measure | Time frame |
|---|---|
| The cortical thickness and microstructure parameters (bone mineral density distribution, porosity, number and size of pores) derived from the HR-pQCT data are comparable to the parameters (porosity, pore size) determined from the CortBS analysis. | — |
Countries
Germany
Contacts
Public ContactGabriele Armbrecht
Charite - Universitätsmedizin Berlin, Campus Benjamin Franklin
Outcome results
None listed