C15.9 C16.9
Conditions
Interventions
Group 1: Three to four blood samples are taken from patients with esophageal adenocarcinoma, esophagogastral junction and stomach. An additional blood sample is taken from patients who develop a relap
Sponsors
Albert-Ludwigs-Universität Freiburg, Medizinische Fakultät-ausführende Stelle: Allgemein- und Vizeralchirurgie
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Ability to understand the content of the study and participate in the research. Signed consent > 18 years Adenocarcinoma of the esophagus, esophagogastral junction or stomach cT1-cT4, Nx, M0 Planned neoadjuvant therapy (chemotherapy or chemoradiation)
Exclusion criteria
Exclusion criteria: Presence of another tumor Chemotherapy or radiochemotherapy already received within the last 3 years.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quantification, morphological and immunophenotypic categorization of CTCs as well as genetic analysis of the CTC-DNA and investigation of the ctDNA and EV for mutations of known tumor-associated genes | — |
Secondary
| Measure | Time frame |
|---|---|
| Description of the circulating tumor cells, ctDNA, EVs and the identified candidate mutations in connection with RFS and OS. | — |
Countries
Germany
Contacts
Public ContactBirte Kulemann
Uniklink Freiburg, Allgemein- und Vizeralchirurgie
Outcome results
None listed