Depressivity, resilience factors and neuroimmunological characterization with special attention to the improvement of psychological well-being

Depressivity, resilience factors and neuroimmunological characterization with special attention to the improvement of psychological well-being - Star*Immun

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00022192

Enrollment

576

Registered

2020-12-21

Start date

2020-09-21

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F32 F33

Interventions

Group 1: Observationgroup 1: Non-depressed patients. For details see Primary and Secondary Outcome above. Group 2: Observationgroup 2: Depressed patients. For details see Primary and Secondary Outcome

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Ability to give consent, written consent

Exclusion criteria

Exclusion criteria: Antisocial personality disorder, severe cognitive limitations e.g. dementia or severe intellectual disability, withdrawal of the declaration of consent

Design outcomes

Primary

Measure	Time frame
Depressive symptoms measured with the Patients Health Questionnaire (PHQ-8). Other measuring instruments: Generalized Anxiety Disorder 7 (GAD-7); Patient Health Questionnaire 15 as somatic symptoms subscale (PHQ-15); Patient Health Questionnaire Stress; Child Trauma Questionnaire (CTQ); Gender minority an resilience measure (GMSR); Rosenberg Self-Esteem Scale (RSES); Self-Rated Successful Aging (SRSA); Internalized Homonegativity Inventory (IHNI); Homopositivity Scale (HPS); Internalized transphobia of the Transgender Identity Survey (TIS-8); Social Support Questionnaire (SSQ6); HIV Stigma-Revision Scale (HIV-Stigma-Revision-12); Community Connectedness from Gender minority an resilience measure (GMSR); Everyday Discrimination Scale (EDS); Resilience Scale (RS10); Internale-Externale-Kontrollu¨berzeugung-4 (IE-4); Big-Five-Inventory-10 (BFI-10); A 6-Item Scale for Overall; Emotional, and Social Loneliness Confirmatory Tests on Survey Data; 8-item index based on the World Health Organization Quality of Life Assessment (Eurohis-QOL); WHO-Five Well-Being Index (WHO-5); Leipzig questionnaire of motives to have a child (LKM).	—

Measure

Time frame

Depressive symptoms measured with the Patients Health Questionnaire (PHQ-8). Other measuring instruments: Generalized Anxiety Disorder 7 (GAD-7); Patient Health Questionnaire 15 as somatic symptoms subscale (PHQ-15); Patient Health Questionnaire Stress; Child Trauma Questionnaire (CTQ); Gender minority an resilience measure (GMSR); Rosenberg Self-Esteem Scale (RSES); Self-Rated Successful Aging (SRSA); Internalized Homonegativity Inventory (IHNI); Homopositivity Scale (HPS); Internalized transphobia of the Transgender Identity Survey (TIS-8); Social Support Questionnaire (SSQ6); HIV Stigma-Revision Scale (HIV-Stigma-Revision-12); Community Connectedness from Gender minority an resilience measure (GMSR); Everyday Discrimination Scale (EDS); Resilience Scale (RS10); Internale-Externale-Kontrollu¨berzeugung-4 (IE-4); Big-Five-Inventory-10 (BFI-10); A 6-Item Scale for Overall; Emotional, and Social Loneliness Confirmatory Tests on Survey Data; 8-item index based on the World Health Organization Quality of Life Assessment (Eurohis-QOL); WHO-Five Well-Being Index (WHO-5); Leipzig questionnaire of motives to have a child (LKM).

—

Secondary

Measure	Time frame
As secondary Outcome collected: blood samples for neurobiological factors such as cytokine, saliva samples and hair samples for cortisol analysis. The aim is to generate a sufficiently large and diverse biobanking for the analysis of group differences.	—

Countries

Germany

Contacts

Public ContactMaximilian Berger

Charité - Universitätsmedizin Berlin Psychiatrische Universitätskliniken der Charité im St. Hedwig-Krankenhaus

maximilian.berger@charite.de030-450-517296

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 14, 2026