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Comparison of different sample types for respiratory microbiome analysis using the ISpro technology

Comparison of different sample types for respiratory microbiome analysis using the ISpro technology - REDALERT-A

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00022094
Enrollment
60
Registered
2020-06-12
Start date
2020-06-16
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J44.9 J18 J45 C34 J84.9 E84

Interventions

Group 1: Part 1: After inclusion, patients choose to contribute one or more of the following samples for a single time: nose swab: a sterile swab is inserted 2-3 cm into one nostril, sideway pressure

Sponsors

Pneumologie/Allergologie, Medizinische Klinik 1, Universitätsklinikum Frankfurt – Goethe-Universität
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Part 1 Written informed consent, In- or outpatient at the Department of Respiratory Medicine, University Hospital Frankfurt, Existing diagnosis of one or more of the following: pneumonia, chronic obstructive pulmonary disease, asthma, lung carcinoma, interstitial lung disease, cystic fibrosis Part 2 Written informed consent, Scheduled bronchoscopy with bronchoalveolar lavage

Exclusion criteria

Exclusion criteria: Suspected or confirmed pulmonary infection with a pathogen of risk group 3 or higher (e.g., Mycobacterium tuberculosis) as published by Committee on Biological Agents / German Federal Institute of Occupational Safety and Health, Inability to understand the nature, scope, and possible consequences of the study

Design outcomes

Primary

MeasureTime frame
First part of the study: Improving the detection of airway bacteria by ISpro technology. Second part of the study: Demonstrate that throat-/ nose-swabs or sputum samples are a viable alternative to bronchoalveolar lavage for analyzing the airway microbiome by ISpro technology

Countries

Germany

Contacts

Public ContactGernot Rohde

Pneumologie/Allergologie, Medizinische Klinik 1, Universitätsklinikum Frankfurt – Goethe-Universität

Gernot.Rohde@kgu.de+49 69 63 01 - 6336

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026