I10 E78 I70
Conditions
Interventions
Group 1: Flavanolrich cocoa (encapsulated), daily for 4 weeks
Group 2: Epicatechin (encapsulated), daily for 4 weeks
Group 3: Methylxanthines (encapsulated), daily for 4 weeks
Group 4: Epicatechin + m
Sponsors
Hochschule Niederrhein, Fachbereich Oecotrophologie
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: BMI: 18,5 – 29,9 kg/m2, non-smoker for at least 3 months, written informed consent
Exclusion criteria
Exclusion criteria: Hypertension, hypercholesterolemia, hypertriglyceridemia, diabetes mellitus, antihypertensiva, lipid-lowering drugs, other medications with influence on vascular markers or lipids, diseases of gastrointestinal tract, kidneys and heart, lymphedema, removal of the axillary lymph nodes, pleuris, paresis, tremor, spasm, venous or arterial vessel accesses and dialysis shunts, cardiac pacemaker, (planned) pregnancy, lactation, planned changes in lifestyle, regular intake of supplements which might affect vascular health and serum lipids
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulse wave velocity, in fasting state before and after 4-wk-intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure, endothelin-1, serum lipids (total cholesterol, LDL-cholesterol, HDL-cholesterol, and triglycerides); in fasting state before and after 4-wk-intervention | — |
Countries
Germany
Contacts
Public ContactJanina Rynarzewski
Hochschule Niederrhein, Fachbereich Oecotrophologie
Outcome results
None listed