I25.19
Conditions
Interventions
Group 1: Cardiotomy suction blood
Group 2: Cell saver blood
Sponsors
Universitätsmedizin Göttingen Klink für Throax-, Herz- und Gefäßchirurgie
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: Isolated CABG with planned more than three grafts. Normal hemoglobin Level. Ejection fraction more than 30%. Normal creatinine and GRF.
Exclusion criteria
Exclusion criteria: Vasoplegic conditions including Sepsis, anaphylactic reactions, haemorrhagic shock, or presence of a peripheral vascular disease. Emergency operations, preoperative mechanical circulatory support, combined procedures or redos. Need for vasoactive substances other than adrenaline, noradrenaline or dobutamine. Need for a transfusion during the intraoperative measurement interval. In case of an intraoperative complication with a significant bleeding of more than 1200 ml the patient will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the effect of cardiotomy suction blood and cell saver blood on the systemic vascular resistance. Prior to declamping the SVR is calculated and then the cardiotomy suction blood or the cell saver blood is transfused. The SVR is then measured again 20, 40 and 60 seconds after the transfusion but still prior to removal of the aortic clamp. | — |
Secondary
| Measure | Time frame |
|---|---|
| Consumption of sympathomimetics as well as postoperative renal function and blood loss. The following parameters will be assessed at arrival to the ICU, 6, 12, and 24 hrs thereafter: Blood loss, serum Creatinine, GFR, dosis of Noradrenaline and Dobutamine. | — |
Countries
Germany
Contacts
Public ContactMichaela Walter
Universitätsmedizin Göttingen Abteilung Kardiotechnik
Outcome results
None listed