Validation of an image based measurement method for the head circumference as an alternative method for diagnosing micro- or macrocephaly

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00021808

Enrollment

100

Registered

2020-05-26

Start date

2020-05-22

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Q02 Q75.3

Interventions

Group 1: Retrospective imaging based measurement of head circumference

Eligibility

Sex/Gender

All

Age

0 Years to 18 Years

Inclusion criteria

Inclusion criteria: Pediatric patients in whom a 3D T1 sequence has been acquired as part of an MRI scan since January 1st 2010 and from whom a head circumference was measured clinically in a timely manner. A deviation of the clinically determined KU from the date of the imaging is permitted by +/- 3 months in children over 6 years of age, by +/- 1 month in children from 2 to 6 years of age and by +/- 1 week in children before the second year of life.

Exclusion criteria

Exclusion criteria: Incomplete imaging or no clinical measurement within the given timespan.

Design outcomes

Primary

Measure	Time frame
Evaluation of the interrater reliability of the retrospective measurement of the head circumference using MRI imaging	—

Secondary

Measure	Time frame
Comparison with the clinically collected data Correlation of the radiologically measured head circumference with the intracranial volume	—

Countries

Germany

Contacts

Public ContactAlexander Rau

UNIVERSITÄTSKLINIKUM FREIBURG, Assistenzarzt - Abt. Neuroradiologie

alexander-rau@uniklinik-freiburg.de076127051790

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026