postoperative pain R52
Conditions
Interventions
Group 1: Axillary Brachial Plexus Block
The patient decides on the anesthesia procedure (regional anesthesia vs. general anesthesia) after consultation / information session with the anesthetist (inf
Sponsors
Universitätsklinikum Gießen und Marburg, Standort Marburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Elective surgery of the hand, forearm and elbow Patients> 18 years Ability to consent and willingness to participate in the study A written declaration of consent is available Sufficient knowledge of German
Exclusion criteria
Exclusion criteria: Patients <18 years or unable to give consent Emergency interventions Refusal to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Integrated pain scores (IPS) within the first 24 hours, calculated from pain scores (NRS 0-10) and cumulative intravenous morphine equivalents (MEQ) in mg. Occurrence of rebound pain, defined as a significantly increased IPS value after the subjectively reported decay of regional anesthesia. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Morphine equivalent consumption (MEQ consumption in milligrams) assuming equianalgesia (comparable pain scores) within the first 24 hours - Pain intensity and evaluation on NRS from 0-10 at rest and during exercise / exercise, every 3 hours within the first 24 hours (NRS-AUC), pain quality on NRS from 0-10) -MEQ in post anesthesia care unit (PACU) -Time to first analgesic request -Peak NRS pain score 0-24 hours, time of peak NRS, number of patients reaching peak NRS 7 -Subgroup analysis in high-risk patients (IPS from +100 to +200), severe pain and high morphine consumption) with regard to the occurrence of 'rebound pain' -Opioid-related side-effects (Opioid-related Symptom Distress Scale, OR-SDS) 0-24 hours -Patient satisfaction (NRS), postoperative recovery (QoR-15, GSR), incidence of PONV, sleep quality 0-24 hours Pain quality with list of pain descriptions (Schmerzbeschreibungsliste, SBL) of the German pain questionnaire (DSF) -Validation of the German translation of the Quality of recovery-15 (QoR-15) questionnaire 0-24 hours Pain intensity and evaluation at rest and when moving (NRS) on sale retrospectively after 1 week Postoperative recovery with the global surgery index (GSI) -Recommendation of the anesthetic procedure (NRS) - frequency of complications (nerve damage, allergic reactions, systemic local anesthetic reactions, surgical complications) -What psychological factors are predestining for the occurrence of 'rebound pain'? -Preoperative assessment of: demographic questions, pain expectations (NRS), pain catastrophization (PCS), optimism (LOT-R), Surgical Fear Questionnaire (SFQ), Patient Health Questionnaire 9 (PHQ-9), General Self-efficacy Scale (GSES) -Validation of the SFQ (a total of 300 patients are required to validate the SFQ, therefore a subsequent amendment, recruitment of patients regardless of the surgical procedure) -Chronified postoperative pain (CPS) follow-up after three months (telephone questionnaire survey), what is | — |
Countries
Germany
Contacts
Public ContactThomas Wiesmann
Philipps Universität MarburgUniversitätsklinkum MarburgKlinik für Anästhesie und Intensivtherapie
Outcome results
None listed