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Serial cross-sectional seroprevalence study of SARS-CoV-2 infection during and after the COVID-19 epidemic in Heidelberg and the Rhein-Neckar region

Serial cross-sectional seroprevalence study of SARS-CoV-2 infection during and after the COVID-19 epidemic in Heidelberg and the Rhein-Neckar region - SARS-CoV-2 seroprevalence study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00021709
Enrollment
1500
Registered
2020-05-18
Start date
2020-07-03
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

SARS-CoV-2 infection U07.1

Interventions

Group 1: Study participants will be asked to come to the clinic three times or alternatively may be visited at home by study personnel. At each visit, a blood sample will be collected and a questionna

Sponsors

Universita¨tsklinikum Heidelberg, Sektion Klinische Tropenmedizin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to No maximum

Inclusion criteria

Inclusion criteria: a) Able to provide a blood sample b) Able to attend the Tropical Medicine clinic for blood draw or be available for a house visit c) In adults, the ability to provide fully informed consent d) Consent from a parent or guardian if the patient is under 18

Exclusion criteria

Exclusion criteria: a) Contraindication to venepuncture b) Age below 5 years of age c) Not able to provide informed consent

Design outcomes

Primary

MeasureTime frame
Age-group specific prevalence of antibodies to SARS-CoV-2 among the general population of Heidelberg and the Rhein-Neckar region.

Secondary

MeasureTime frame
1) Age-group specific cumulative incidence during the epidemic compared to the end of the epidemic (post-epidemic) or according to local COVID-19 epidemiology. 2) Association of risk factors / protective measures recorded on the questionnaire and evidence of SARS-CoV-2 infection (SARS-CoV-2 antibodies). 3) Proportion of asymptomatic / sub-clinical SARS-CoV-2 infections.

Countries

Germany

Contacts

Public ContactClaudia Maria Denkinger

Universitätsklinikum Heidelberg, Sektion Klinische Tropenmedizin

Claudia.Denkinger@uni-heidelberg.de062215622999

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026