L82
Conditions
Interventions
Group 1: 532nm-Laser (LBO)
Group 2: curettage
Group 3: cryospray
Sponsors
Praxis Prof. Krengel/ Haase/ Mrowka
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) The patient is at least 18 years old. 2) The clinical diagnosis of seborrheic keratosis is confirmed. 3) The patient has at least three seborrheic keratoses suitable for treatment. 4) The patient is not pregnant and is not breastfeeding. 5) The patient is in good health with no current ailments. This includes other skin diseases that could affect the assessment of a target lesion or place the patient at risk of complications. 6) The patient is able to follow study instructions and participate in all study appointments. 7) The patient is able to understand and sign the declaration of consent.
Exclusion criteria
Exclusion criteria: 1) The patient has an atypical seborrheic keratoses where the diagnosis is uncertain. 2) The patient is pregnant and / or breastfeeding. 3) The patient has a skin disease that is either flurid or not controlled (e.g. psoriasis, eczema) or a skin condition (sunburn) which, in the opinion of the investigator, would impair the condition or endanger the patient if he or she participated in the study. 4) The patient used one of the following systemic therapies within the specified period (30 days) before enrollment: retinoids, glucocorticosteroids, Anti-metabolites. (e.g. methotrexate) 5) The patient received one of the following therapies within the specified period of time or close to the target lesion: laser, light or other energy-based therapy (e.g. intense pulsed light, photodynamic therapy; liquid nitrogen, electrode cauterization), Curettage, imiquimod, 5-flurouracil or ingenol mebutate, retinoids, microdermabrasion or superficial chemical peels, topical or systemic glucocorticosteroids, antibiotics. 6)The patient has presented with a cutaneous malignancy, a pre-malignancy (e.g actinic keratosis), sunburn, an excessive tan or body art (tattoos, piercing, etc) as this may have a detrimental effect on treatment outcomes or hinder pre and post-treatment analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient satisfaction: "Which of the three methods would the patient prefer for future treatment?" The primary outcome is assessed via questionnaire at the day of the treatment of the patient and after 4, 8 and 12 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare healing rates and record the medical assessment of the results at the day of the treatment and after 4, 8 and 12 weeks. Furthermore ask a blinded observer at the end of the study via photographic recordings about the best outcome. | — |
Countries
Germany
Contacts
Public ContactVanessa Timmermann
Hautpartner
Outcome results
None listed