E66.9
Conditions
Interventions
Group 1: Overweight children and adolescents
In addition to regular non-invasive blood pressure measurement and registration of the heart rate during general anaesthesia, each participant will have a
Sponsors
Universitätsklinikum Leipzig AöR; Klinik und Poliklinik für Anästhesiologie und Intensivtherapie
Eligibility
Sex/Gender
All
Age
6 Years to 16 Years
Inclusion criteria
Inclusion criteria: Consent of legal guardians; anaesthesia in the operative field of paediatric surgery/orthopaedics; ASA I + II; operation time > 45 min
Exclusion criteria
Exclusion criteria: rejection by legal guardians; ASA III + IV; requirement for rapid sequence induction; intraoperative administration of catecholamines; long-term therapy with steroids, opioid analgesics and/or sedatives; tumor diseases; participation in another clinical study; critically ill child (intensive care); presence of pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The aim of the study is to investigate the influence of propofol on blood pressure and on various endogenous hormonal regulatory mechanisms (renin-angiotensin-aldosterone system, vasopressin system, catecholamines) in children and adolescents as a function of BMI. | — |
Secondary
| Measure | Time frame |
|---|---|
| A further aim is to clarify whether overweight or obese children/adolescents have less or more blood pressure drops than normal weight patients during general anaesthesia with Propofol? For this purpose, the non-invasive blood pressure values regularly measured during general anaesthesia are evaluated. | — |
Countries
Germany
Contacts
Public ContactClaudia Höhne
DRK Kliniken Berlin Köpenick; Klinik für Anästhesie, Schmerztherapie, Intensiv- und Notfallmedizin
Outcome results
None listed