N97 F43
Conditions
Interventions
Group 1: A total of 60 patients will be randomized into two treatment groups: the group receiving midazolam premedication, and the control group that does not. Standard treatment (golden standard) is
Sponsors
Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center Sestre milosrdnice, Zagreb, Croatia School of Medicine, University of Zagreb, Šalata 3, 10000 Zagreb, Croatia
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: The study includes healthy women over 18 years of age that are planned for oocyte aspiration as part of an IVF procedure.
Exclusion criteria
Exclusion criteria: Incomplete follow-up and failure to obtain informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome measures will be levels of stress markers in the serum and follicular fluid prior to midazolam administration, immediately prior to oocyte aspiration and 2 hours after aspiration. | — |
Secondary
| Measure | Time frame |
|---|---|
| As a secondary outcome, the number of successful pregnancies will be recorded during post-procedural follow up, defined as beta HCG values increase and ultrasound confirmation of pregnancy 8 weeks after the procedure. | — |
Countries
Croatia
Contacts
Public ContactAndro Košec
Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center Sestre milosrdnice, Zagreb, Croatia School of Medicine, University of Zagreb, Šalata 3, 10000 Zagreb, Croatia
Outcome results
None listed