F20
Conditions
Interventions
Group 1: Individualized Exercise Plan: focus on the three most impaired cognitive functions of the schizophrenic patients (n = 20)
Group 2: Generic Exercise Plan: target the same set of six cognitive
Sponsors
Abteilung für Psychiatrie und Psychotherapie SRH Klinikum Karlsbad-Langensteinbach
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: (1) Patients should meet DSM-IV criteria for schizophrenia (295.1-295.3; 295.6; 295.9) confirmed with the MINI (2) Age between 18 and 55 years (3) IQ> 80 according to the Mehrfachwahl-Wortschatztest (4) No current substance abuse (standard drug screening in urine) (5) No documented or suspected major brain damage or other neurological diseases (e.g. stroke, epilepsy, concussion) (6) Patients must be clinically stable and able to provide informed consent
Exclusion criteria
Exclusion criteria: (1) Patients with Positive and Negative Syndrome Scale scores = 5 for any positive symptom item will be excluded to avoid confounding with acute psychotic symptoms (2) Patients with Hamilton Rating Scale for Depression scores = 20 will be excluded to avoid confounding with severe depressive symptoms (3) Cognitive deficits: in at least three domains scores below PR<16 (WAFA, WAFG, WAFS, NBV, ToL, Go/NoGo)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neuropsychological performance, psychopathology and functional outcome were assessed at baseline and post-treatment. Psychopathology und demographics: PANSS, HAMD, M.I.N.I-SKID (only baseline), BDI, MWT-B (only baseline) Functional outcome: GAF, MINI-ICF-APP, SLOF Neuropsychological performance: alertness, divided attention, selective attention, working memory, planning, response inhibition | — |
Countries
Germany
Contacts
Public ContactMatthias Weisbrod
Abteilung für Psychiatrie und Psychotherapie SRH Klinikum Karlsbad-Langensteinbach
Outcome results
None listed