nociceptive flexion reflex threshold (NFRT) Opioid dosing
Conditions
Interventions
Group 1: Characterisation of stimulation threshold of a nociceptive flexion reflex (NFRT) during the course of a cardiosurgical operation (pre- vs. post-operatively).
Sponsors
Universitätsklinik für Anästhesiologie, Intensivmedizin, Notfallmedizin, SchmerztherapieKlinikum Oldenburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Elective cardiac surgery at Klinikum Oldenburg, at minimum 18 years of age, informed written consent
Exclusion criteria
Exclusion criteria: Age below 18, no written informed consent, non-elective patients, insufficient German language skills, pregnancy or childbirth within the last four weeks, preexisting medical conditions of: chronic pain, polyneuropathy, injured or otherwise compromised CNS, chronic use of opioids or benzodiazepines for longer than two weeks within the last six months, anatomical conditions which prevent NFRT measurement, any electric implants (i.e. ICD, pacemaker, neurostimulators), score at tuning fork test < 6
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Course of nociceptive flexion reflex threshold (NFRT) over time | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain (NRS, BPS), delirium (CAM-ICU), cardiovascular system (heart rate, blood pressure), length of ventilation, opioid dosage, nausea/ vomiting (PONV) | — |
Countries
Germany
Contacts
Public ContactUlf Günther
Universitätsklinik für Anästhesiologie, Intensivmedizin, Notfallmedizin, SchmerztherapieKlinikum Oldenburg
Outcome results
None listed