G40.2
Conditions
Interventions
Group 1: Tapering of medication three months after epilepsy surgery following a fixed scheme
Group 2: Continuation of anticonvulsive pharmacotherapy and start with tapering of medication twelve months
Sponsors
Universitätsklinikum Göttingen Klinik für Anästhesiologie Klinik für Neurologie
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Resective epilepsy surgery - preoperative seizure frequency = 1 seizure per month - immediate postoperative seizure freedom for at least 3 months
Exclusion criteria
Exclusion criteria: - Epileptic seizures within the first 3 months after epilepsy surgery - Participation in a clinical trial on an anticonvulsive drug - Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of patients per group (tapering off medication 3 months vs. 12 months after epilepsy surgery) who are seizure-free 24 months after epilepsy surgery without anticonvulsive medication | — |
Secondary
| Measure | Time frame |
|---|---|
| - Number of patients per group (tapering off medication 3 months vs. 12 months after epilepsy surgery) who are seizure-free 24 months after epilepsy surgery with anticonvulsive medication - Number of patients per group (tapering off medication 3 months vs. 12 months after epilepsy surgery) who are not seizure-free 24 months after epilepsy surgery with anticonvulsive medication - Time until the first epileptic seizure recurs from begin of reduction of medication onwards - Number of patients suffering a relapse during the time of tapering medication - Clinical factors associated with the reoccurrence of epileptic seizures | — |
Countries
Germany
Contacts
Public ContactCaspar Stephani
Universitätsklinikum Göttingen Klinik für Anästhesiologie Klinik für Neurologie
Outcome results
None listed