Comparative study of the intraoral and carotid plaque microbiome in patients with carotid stenosis: Analysis of the metagenome and metatranscriptome

Comparative study of the intraoral and carotid plaque microbiome in patients with carotid stenosis: Analysis of the metagenome and metatranscriptome - Perio_Carotis_Micro

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00021598

Enrollment

Registered

2020-05-14

Start date

2020-03-03

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I63.2 I65.2 K05.1 K05.2 K05.3 K05.4 K05.0

Interventions

Group 1: • Number of study participants - 30 patients • Inclusion criteria - Inpatients with obstructive arterial disease and planned endarterectomy of the carotid artery - Age: = 35 years - At lea

Eligibility

Sex/Gender

All

Age

35 Years to No maximum

Inclusion criteria

Inclusion criteria: - Inpatients with obstrucive arterial disease and planned endarterectomy of the carotid artery - Age: = 35 years - At least 4 natural teeth - German Caucasian origin - no relationship between the study participants

Exclusion criteria

Exclusion criteria: - subgingival PA therapy within 6 months prior to sample collection - systemic antibiotic therapy within 3 months before sample collection - Pregnancy/nursing period

Design outcomes

Primary

Measure	Time frame
Characterization of the intraoral microbial metagenome and metatranscriptome in patients with arterial obstructive disease of the carotid artery as a function of the pardontal status	—

Secondary

Measure	Time frame
Comparative study of the microbial metagenome and metatranscriptome intraorally and in cell material of the carotid artery.	—

Countries

Germany

Contacts

Public ContactSusanne Schulz

Martin-Luther-Universität Halle-Wittenberg Universitätspoliklinik für Zahnerhaltungskunde und Parodontologie

susanne.schulz@medizin.uni-halle.de+49-345-557 1147

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026