Haemodynamic effects of propofol/remifentanil anesthesia induction on cardiac preload, afterload, and contractility - a prospective observational study

Haemodynamic effects of propofol/remifentanil anesthesia induction on cardiac preload, afterload, and contractility - a prospective observational study - HEPRI Haemodynamic Effects Propofol Remifentanil Induction

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00021596

Enrollment

Registered

2020-08-26

Start date

2010-09-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

INTRAOPERATIVE HYPOTENSION

Interventions

Group 1: Patients undergoing propofol/remifentanil anesthesia induction will be investigated before and after induction of anesthesia.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients scheduled for major abdominal surgery with indication for extended hemodynamic Monitoring (PiCCO, invasiv blood pressure, CVC).

Exclusion criteria

Exclusion criteria: Prior vascular surgery of the femoral artera, pneumonectomy, aortic aneurysm, heart valve disease, left-ventricular ejection fraction below 40%

Design outcomes

Primary

Measure	Time frame
Changes in global end-diastolic volume index (GEDI)	—

Secondary

Measure	Time frame
Mean arterial pressure, Cardiac index, dPmx, Global ejection fraction	—

Countries

Germany

Contacts

Public ContactAndreas Weyland

Universitätsklinik für Anästhesiologie (AINS) Klinikum Oldenburg AöR

weyland.andreas@klinikum-oldenburg.de0441-4032571

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026