Investigation of the predictive value of coagulation parameters for the course of disease in COVID-19 patients

Investigation of the predictive value of coagulation parameters for the course of disease in COVID-19 patients - COVID_coagulation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00021574

Enrollment

1000

Registered

2020-05-19

Start date

2020-04-08

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

U07.1

Interventions

Group 1: Determination of coagulation status in patients with COVID-19 at day 1 and 7 of hospitalization

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: -at least 18 years old - hospitalisation with suspected or confirmed COVID-19 diagnosis

Exclusion criteria

Exclusion criteria: -younger than 18 years

Design outcomes

Primary

Measure	Time frame
Blood sampling (6 ml Plasma) at day 1 and 7 of hospitalization: determination of Quick, PTT, fibrinogen, D-dimer, antithrombin, hs-troponin, coagulation factors und VWF-antigen, Protein C und Protein S, thrombin generation, plasminogen-activator inhibitor-Type 1	—

Secondary

Measure	Time frame
-clinical symptoms -type and duration of antikoagulation -Therapy (medication, heparin, oxygen, NIV/IV, ECLS) -duration of hospitalization -Outcome (morbidity, mortality) -Co-morbidities and medication Additional data will be documented in CRF about: sex, age, secondary infections (viral, bacterial), SOFA Score, small blood count, CRP	—

Countries

Germany

Contacts

Public ContactWolfgang Miesbach

Hämophiliezentrum, Institut für Transfusionsmedizin, Medizinische Klinik III, Goethe Universitätsklinikum

wolfgang.miesbach@kgu.de06963015051

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026