Prism adaptation based therapy: dosis and effects

Prism adaptation based therapy: dosis and effects - PANDEF

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00021539

Enrollment

Registered

2020-04-30

Start date

2020-05-14

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R29.5

Interventions

Group 1: Intervention A: intermittent prism adaptation therapy. The first task (during 8 minutes) is performed with prism glasses. Then the second task follows for 8 minutes without glasses. Then the

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - minimum age of 18 years - left-sided neglect after right hemispheric lesion - sufficient capacity to be mobilized for at least 30 minutes - regular participation in at least 80% of the planned therapies

Exclusion criteria

Exclusion criteria: - presence of premorbid dementia - normal pressure hydrocephalus - regular participation in less than 80% of the planned therapies

Design outcomes

Primary

Measure	Time frame
Apple Cancellation Task (Bickerton, Samson, Williamson, & Humphreys, 2011): The measurements are performed at four measurement points: T1 = Day 1 of recruitment T2 = 2 days later (to avoid retest effects) T3 = after completion of the first intervention T4 = after completion of the second intervention Description of the task: Cross-out task on an A4 sheet where the patient should ignore apples with left or right side holes and only cross out the apples without such holes. The test contains a total of 50 apples to be crossed out. Both room-based (omitting full apples on the neglected room side) and object-based neglects symptoms (false-positive ticking of apples that are open on the left side, regardless of their position on the sheet) are assessed. 2. Functional Independence Measure (FIM) and Early Rehabilitation Barthel Index (ERBI). The measurements take place at three measurement points: T1 = day 1 of recruitment T3 = after completion of the first intervention T4 = after completion of the second intervention In order to measure difficulties in everyday life, the hospital staff evaluates the patient's nursing effort on a weekly basis.	—

Measure

Time frame

Apple Cancellation Task (Bickerton, Samson, Williamson, & Humphreys, 2011): The measurements are performed at four measurement points: T1 = Day 1 of recruitment T2 = 2 days later (to avoid retest effects) T3 = after completion of the first intervention T4 = after completion of the second intervention Description of the task: Cross-out task on an A4 sheet where the patient should ignore apples with left or right side holes and only cross out the apples without such holes. The test contains a total of 50 apples to be crossed out. Both room-based (omitting full apples on the neglected room side) and object-based neglects symptoms (false-positive ticking of apples that are open on the left side, regardless of their position on the sheet) are assessed. 2. Functional Independence Measure (FIM) and Early Rehabilitation Barthel Index (ERBI). The measurements take place at three measurement points: T1 = day 1 of recruitment T3 = after completion of the first intervention T4 = after completion of the second intervention In order to measure difficulties in everyday life, the hospital staff evaluates the patient's nursing effort on a weekly basis.

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Secondary

Measure	Time frame
1. The following measurements take place at four measuring points: T1 = day 1 of recruitment T2 = 2 days later (to avoid retest effects) T3 = after completion of the first intervention T4 = after completion of the second intervention Measurements: - Text reading assessment - Line bisection - Clock test Questionnaire: - Body positioning (when seated) 2. EEG measurements of the event related potentials (EKP). The EEG measurements take place at three measuring points: T1 = day 2 of recruitment T3 = after completion of the first intervention T4 = after completion of the second intervention	—

Measure

Time frame

1. The following measurements take place at four measuring points: T1 = day 1 of recruitment T2 = 2 days later (to avoid retest effects) T3 = after completion of the first intervention T4 = after completion of the second intervention Measurements: - Text reading assessment - Line bisection - Clock test Questionnaire: - Body positioning (when seated) 2. EEG measurements of the event related potentials (EKP). The EEG measurements take place at three measuring points: T1 = day 2 of recruitment T3 = after completion of the first intervention T4 = after completion of the second intervention

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Countries

Germany

Contacts

Public ContactHelmut Hildebrandt

Zentrum für Neurologie, Klinikum Bremen-Ost

Helmut.Hildebrandt@klinikum-bremen-ost.de00494214081599

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 14, 2026