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Intestinal permeability in glomerular diseases

Intestinal permeability in glomerular diseases

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00021533
Enrollment
70
Registered
2020-04-24
Start date
2017-06-23
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

N05 N00-N08

Interventions

Group 1: Glomerulonephritis patients and healthy controls receive a single oral load with a sugar solution (lactulose, L-rhamnose, sucralose and erythritol). At 2, 5 and 24 hrs after ingestion, the ur

Sponsors

Universitätsklinikum der RWTH Aachen
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Biopsy-proven primary glomerulonephritis or no prior renal disease (healthy controls). Able to consent.

Exclusion criteria

Exclusion criteria: History of chronic gastrointestinal diseases, signs of acute infection, diabetes mellitus, end-stage renal disease, or intake of non-steroidal anti-inflammatory drugs (NSAID) during the last 48 hours prior to the study as well as pregnant and breast-feeding patients

Design outcomes

Primary

MeasureTime frame
Urinary excretion of the various sugars (lactulose, L-rhamnose, sucralose and erythritol) at 2, 5, 24 hrs after oral ingestion

Countries

Germany

Contacts

Public ContactJürgen Floege

Universitätsklinikum der RWTH Aachen

jfloege@ukaachen.de0241-8089530

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 11, 2026