J80 B97 F05 N17
Conditions
Interventions
Group 1: Adult male or female patients with evidence of SARS-CoV2 in the nose or throat swab or in the bronchoalveolar lavage and the need for intensive care therapy due to acute respiratory failure
Sponsors
Universitätsklinik Freiburg, Klinik für Anästhesiologie und Intensivmedizin
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Adults (> 18 years) male or female patient; 2. Detection of SARS-CoV2 in the nose or throat swab or in the bronchoalveolar lavage; 3. Need for intensive care therapy in the intensive care unit; 4. Ability to consent, either personally or through an authorized person/proxy
Exclusion criteria
Exclusion criteria: 1. children <18 years; 2. Patients with congenital immune defects; 3. Patients with pre-existing cognitive impairment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Contingency table: mRS categories vs. inflammation high / inflammation low categories | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammation high/ low categories vs. rate of delirium, expression of circadian genes, duration of sedation and ventilation, rate of kidney failure, rate of thrombembolic events, ICU length of stay, survival, quality of life after 6 months. | — |
Countries
Germany
Contacts
Public ContactNils Schallner
Universitätsklinik Freiburg, Klinik für Anästhesiologie und Intensivmedizin
Outcome results
None listed