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COVID-19 associated brainstem encephalitis - is SARS-CoV-2 a neurotropic agent?

COVID-19 associated brainstem encephalitis - is SARS-CoV-2 a neurotropic agent?

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00021439
Enrollment
70
Registered
2020-04-20
Start date
2020-04-20
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19 U07.1

Interventions

Group 1: Observation group: All patients with a focal-neurological deficit and positive SARS-CoV-2 PCR who are in the Freiburg University Hospital for Treatment or are presented on an outpatient basis

Sponsors

Klinik für Neurologie und Neurophysiologie Universitätsklinikum Freiburg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age > 18 Years Proof of SARS-CoV-2 Infection Anamnestic Anosmia/Ageusia Clinical or radiological indication of encephalitis in COVID-19 disease

Exclusion criteria

Exclusion criteria: Lack of possibility for oral and written patient information

Design outcomes

Primary

MeasureTime frame
Predictive value of the clinical symptoms ageusia and anosmia for a negative outcome of COVID-19 disease and for the detection of changes in the brain, meninges and cerebrospinal fluid in the instrumental diagnostics.

Secondary

MeasureTime frame
• Correlation between the results of different diagnostic procedures and the clinical course • Correlation between the results of various diagnostic procedures and vital parameters and, if applicable, ventilation parameters and clinical findings • Death from COVID-19 disease • Further research questions are derived in the course of the project

Countries

Germany

Contacts

Public ContactJonas Hosp

Klinik für Neurologie Universitätsklinikum Freiburg

jonas.hosp@uniklinik-freiburg.de0761-270-50010

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026