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Covid-19 Case-Cluster-Study

Covid-19 Case-Cluster-Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00021306
Enrollment
1400
Registered
2020-04-14
Start date
2020-03-31
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19 U07.1

Interventions

Group 1: Index persons of the Gangelt register as well as household or family members: Collection of biological samples for virus diagnostics from the study participants: - adults: 3 EDTA tubes (10 ml

Sponsors

Institut für Virologie/ Universitätklinikum Bonn
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Residence in the Heinsberg district - Individual surname and random selection as index person (by sampling from the Gangelt municipal register) - For the substudy: participation in the “Kappensitzung” - Household or family members of the index person/participants of the "Kappensitzung"

Exclusion criteria

Exclusion criteria: None.

Design outcomes

Primary

MeasureTime frame
The primary endpoint is the prevalence of SARS/CoV-2 positive individuals in the study population, defined as the number of individuals with positive laboratory findings (from at least one of the sample media collected in the study) divided by the total number of study participants.

Secondary

MeasureTime frame
Secondary endpoints are (i) the "level of infestation", defined as the sum of a. prevalent persons, and b. healthy individuals with previous positive laboratory findings (prior to the conduct of the study) with concurrent negative laboratory findings in the study, divided by the total number of study participants, (ii) the rate of unreported cases, defined as the number of persons with positive laboratory results (in the study) but without previous positive laboratory results (before the study was conducted), divided by the total number of study participants, (iii) the proportion of healthy individuals, defined as the number of individuals with previous positive laboratory results (before the study was conducted) with concurrent negative laboratory results in the study, divided by the total number of study participants, (iv) the associations of the above measures with the symptoms reported in the questionnaire, (v) the associations of the above measures with the personal factors recorded in the questionnaire, (vi) the associations of the above measures with the personal and behavioural factors recorded in the expanded questionnaire; and (vii) the associations of the above measures with the additional environmental factors collected in the selected households

Countries

Germany

Contacts

Public ContactHendrik Streeck

Institut für Virologie/ Universitätklinikum Bonn

Hendrik.Streeck@ukbonn.de022828715522

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026