Posttraumatic stress disorder (DSM-5) after abuse/maltreatment in childhood/adolescence F43.1
Conditions
Interventions
Group 1: Therapy group 1: STAIR Narrative Therapy with PTSD-CM patients (24 therapy sessions according to manual
see also DRKS00021142)
examination before and after therapy as well as 6 month after finishing therapy
Group 2: Therapy group 2: trauma focused psychodynamic therapy with PTSD-CM patients (24 therapy sessions according to m
examination before and after therapy as well as 6 month after finishing therapy
Group 3: Waitinglist control group (minimal attention waiting list
see also DRKS00021142) of patients with PTSD-CM
first, 6 month waiting period and examination before and after therapy
then, STAIR Narrative therapy or trauma-focused psychodynamic therapy, like arm 1 and 2, respectively
in order to achieve a sufficient sample size, additional patients were recruited for the waiting list control group, who subsequently were offered cognitive behavioral therapy
Group 4: mentally health
no intervention
examination before and after 6 month like the waitinglist control group
Group 5: mentally healthy participants without traumatic experiences
examination before and after 6 month like the waitinglist control group
Sponsors
Justus-Liebig-Universität Gießen
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with PTSD-CM: Adults with posttraumatic stress disorder (PTSD) following child maltreatment, which had been inflicted upon them by a caregiver or authority figure before the age of 18. Ongoing stable medication since 3 months is allowed. Healthy controls: adults with experience of an equivalent trauma during childhood or youth, but without PTSD-diagnosis or any other mental disorder; as well as adults without trauma experience and without any psychological disorder.
Exclusion criteria
Exclusion criteria: PTSD-CM patients: psychotic disorders, suicidality, ongoing maltreatment, acute substance abuse disorder, borderline personality disorder, dissociative identity disorder, organic brain disease, serious physical illness, current psychotherapeutic treatment, current psychopharmacological medication < 3 months stable, standard MRI-exclusion criteria; Healthy controls: any psychological disorder, current psychotherapeutic or psychiatric treatment, serious physical illness, standard MRI exclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time of measurement: pre, post and follow up (follow up without waitlist control group); Experimental research question (MRI): Blood oxygen level dependent (BOLD) response in amygdala, insula, hippocampus, ACC, PFC; Brain structural research question: grey matter volume (hippocampus, amygdala, PFC, ACC); fractional anisotrophy (corpus callosum, uncinate fasciculus, cingulum, superior longitudinal fasciculus); Pattern seperation task (stimulus discrimination): pattern seperation index | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of Measurement: pre, post and follow-up (follow up without waitinglist control group): Reaction times und affect ratings; explorative whole brain analysis; skin conductance response | — |
Countries
Germany
Contacts
Public ContactAnn-Kathrin Noll
Professur für Psychotherapie und Systemneurowissenschaften, Fachbereich Psychologie und Sportwissenschaften, Justus-Liebig-Universität Gießen
Outcome results
None listed