K74.0 K74.1 C22.0 C78.7 K70 K73 K75 K76
Conditions
Interventions
Group 1: In patients with indicated and planned laparotomy, the degree of rigidity of the liver is measured intraoperatively in vivo on healthy organs and ex vivo on pathologically altered resectates
Sponsors
Universitätsklinik für Viszeralchirurgie - PIUS-Hospital Oldenburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Age of majority - indicated laparotomy, if an adequate measurement can be made under the given surgical incision - Period: April 2020 to April 2021
Exclusion criteria
Exclusion criteria: - Minority - Cases outside the period from April 2020 to April 2021 - Insufficient knowledge of the German language - Refusal to participate in the study - Withdrawal at the request of the patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rigidity of healthy and abnormally changed livers in vivo in indicated laparotomies as well as ex vivo from resected parts of the liver, measured by durometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| - correlation between liver rigidity and the Hounsfield scale or values extracted from the MRI sequences - correlation between liver rigidity and different liver-specific laboratory values (alanine aminotransferase (ALT, ALAT)/glutamate pyruvate transaminase (GPT), aspartate aminotransferase (AST)/glutamate oxaloacetate transaminase (GOT), gamma-glutamyltransferase (gamma-GT), alkaline phosphatase (AP), lactate dehydrogenase (LDH), alpha-foetoprotein (AFP), bilirubin (direct, indirect), quick value / INR, antithrombin, platelets, ammonia, albumin, cholinesterase, hepatitis serology, serum ferritin) - Relation between liver hardness and liver diseases (hepatitis, HCC, liver cirrhosis, sclerosing cholangitis, alveolar echinococcosis, cystic echinococcosis) | — |
Countries
Germany
Contacts
Public ContactDaniela Salzmann
Universitätsklinik für Viszeralchirurgie Universitätsmedizin Oldenburg, Pius-Hospital Oldenburg
Outcome results
None listed