Investigation of reported pain intensities and symptoms of stress in formerly ventilated internistic patients on intensive care unit – a prospective observational study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00021112

Enrollment

100

Registered

2020-03-23

Start date

2020-08-03

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R52.0

Interventions

Group 1: we investigate formerly ventilated internistic patients on intensive care unit with respect to their remembered pain sensation during ventilation and weaning as well as the duration of artifi

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: patients that had to be ventilated artificially due to an internistic indication. Adult patients. Informed consent.

Exclusion criteria

Exclusion criteria: patients under 18 years. Missing informed consent. Chronic pain patients with ongoing opioid therapy. Delirium.

Design outcomes

Primary

Measure	Time frame
Primary endpoint: remembered pain intensity of patients during ventilation/ weaning; inquiry 2 - 6 days after Extubation with numeric rating scale	—

Secondary

Measure	Time frame
-differences in pain intensity during the period of artificial ventilation with respect to aspects of opioid therapy -symptoms of posttraumatic stress (PTSS-10) -symptoms of depression (Depression, Anxiety and Stress Scale) -satisfaction with pain therapy -symptoms of delirium (CAM-ICU) -quality of life (SF-12) development of opioid-induced hyperalgesia/opioid tolerance (Quantitative Sensory Testing) Data assessment: 2 - 6 days after extubation	—

Measure

Time frame

-differences in pain intensity during the period of artificial ventilation with respect to aspects of opioid therapy -symptoms of posttraumatic stress (PTSS-10) -symptoms of depression (Depression, Anxiety and Stress Scale) -satisfaction with pain therapy -symptoms of delirium (CAM-ICU) -quality of life (SF-12) development of opioid-induced hyperalgesia/opioid tolerance (Quantitative Sensory Testing) Data assessment: 2 - 6 days after extubation

—

Countries

Germany

Contacts

Public ContactJohannes Loeser

Zentrum für Palliativmedizin, Uniklinik Köln

johannes.loeser@uk-koeln.de0049-221-478-87526

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026