Skip to content

Retrospective monocentric cohort study to evaluate the efficacy and safety of Splentis for transvaginal sacrospinal fixation of the primary apical prolapse

Retrospective monocentric cohort study to evaluate the efficacy and safety of Splentis for transvaginal sacrospinal fixation of the primary apical prolapse - Rexo

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00021072
Enrollment
160
Registered
2021-03-16
Start date
2020-06-08
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

N81.4

Interventions

Group 1: Women, who underwent bilateral sacrospinous hysteropexy with splentis for apical prolapse will be retrospectively enrolled and anatomical results (at last clinical follow up) as well quality

Sponsors

Promedon GmbH
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. women = 18 Jahre 2. History of transvaginal bilateral sacrospinal fixation by splentis of an apical pelvic organ prolapse 3. Signed informed consent

Exclusion criteria

Exclusion criteria: 1. Patient is unwilling or capable of giving informed consent

Design outcomes

Primary

MeasureTime frame
Cure from apical and anterior pelvic organ prolapse. Cure is defined according POP-Q = 1 at the time of last follow-Up

Secondary

MeasureTime frame
1) Number of Patients with improvement of quality of life according the german questionnaire (deutscher Beckenbodenprolaps Fragebogen) 2) Number of adverse events 3) Number of patients with pain as well as severity categoriation according visual analogue scale of pain. 4) Number of patients who are satisfied with the intervention 5) Number of surgical revisions as well as estimated revision and explantation free survival according Kaplan Meier 6) Estiamted recurrent free survival according kaplan-meier

Countries

Germany

Contacts

Public ContactAndreas Spicker

Promedon GmbH

Trials.de@promedon.com+498031900400

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026