Is VIM-DBS in ET-plus patients as effective as in ET patients?

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00021068

Enrollment

Registered

2021-05-03

Start date

2019-07-27

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G25.0

Interventions

Group 1: Patients with thalamic DBS are retrospective classified in ET and ET-plus. Tremor is analyzed before and after DBS in stimulation-OFF and -ON and amount of tremor reduction is calculated and

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: ET patients with VIM/PSA-DBS, implantation at our center (Universitiy Hospital of Cologne), preoperative written and video documentation that allows classification in either ET or ET-plus

Exclusion criteria

Exclusion criteria: Insufficient preoperative documentation that would allow classification in ET and ET-plus, DBS-implantation less than 3 months ago

Design outcomes

Primary

Measure	Time frame
DBS-response (%) measured via TRS in ON vs OFF Point of time is variable as it is mainly a retrospective study.	—

Secondary

Measure	Time frame
TRS-ON-Score of ET-plus vs ET. Point of time is not defined due to the retrospective character of the study	—

Countries

Germany

Contacts

Public ContactJulia K. Steffen

Klinik und Poliklinik für Neurologie, Uniklinik Köln

julia.steffen@uk-koeln.de+492214784013

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026