Fluid responiveness in patients with extracorporeal membrane oxygenation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00021050

Enrollment

Registered

2020-03-30

Start date

2019-11-26

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J80.0

Interventions

Group 1: Comparative examination with echocardiography and thermodilution/pulse conture analysis with regard to fluid responsiveness (measured by passive leg raise test).

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with ECMO with stable oxygenation (paO2=55mmHg, SaO2>=88%), hemodynamic stability (MAP>=65mmHg, Cardiac Index >=2,5L/min/m^2)

Exclusion criteria

Exclusion criteria: kongenital heart defects, severe valvular dysfunction or severe arrhythmia, life expectancy <24h, contraindications for TEE

Design outcomes

Primary

Measure	Time frame
Fluid responsiveness (yes/no) measured by respiratory variation of the superior vena cava vs. fluid responsiveness (yes/no) predicted by a passive leg raise test at the timepoint of measurement during therapy with extracorporeal membrane oxygenation.	—

Secondary

Measure	Time frame
Fluid responsiveness (yes/no) measured by respiratory variation of the superior vena cava vs. fluid responsiveness (yes/no) predicted by pulse contour analysis at the timepoint of measurement during therapy with extracorporeal membrane oxygenation.	—

Countries

Germany

Contacts

Public ContactGregor Loosen

Universitätsmedizin Mannheim

joerg.krebs@umm.de0621-3833233

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 22, 2026