Blood measurement of perioperative oxidative stress in patients undergoing cardiac surgery

Blood measurement of perioperative oxidative stress in patients undergoing cardiac surgery - BESTOX

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00021047

Enrollment

100

Registered

2020-08-28

Start date

2020-10-27

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

perioperative, antioxidative stress

Interventions

Group 1: From patients undergoing cardiac surgery blood samples are drawn at 5 different times (preoperative, intraoperative, on admission to intensive care unit, first postoperative day in intensive

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: cardiac surgery at the University Heart Center Freiburg - Bad Krozingen

Exclusion criteria

Exclusion criteria: patients unable to give consent, minors

Design outcomes

Primary

Measure	Time frame
concentration of free radicals postoperatively in relation to the preoperatively measured concentration	—

Secondary

Measure	Time frame
mortality, usage of catecholamines and vasoactive drugs, days on intensive care unit, days in hospital, incidence of wound healing disorder, duration of invasive ventilation, duration of non-invasive ventilation, total duration of ventilation, concentration of endogen antioxidants postoperatively in relation to the preoperatively measured concentration, incidence of postoperative infections, total days of treatment with anti-infectives	—

Measure

Time frame

mortality, usage of catecholamines and vasoactive drugs, days on intensive care unit, days in hospital, incidence of wound healing disorder, duration of invasive ventilation, duration of non-invasive ventilation, total duration of ventilation, concentration of endogen antioxidants postoperatively in relation to the preoperatively measured concentration, incidence of postoperative infections, total days of treatment with anti-infectives

—

Countries

Germany

Contacts

Public ContactJan-Steffen Pooth

Universitäts-Herzzentrum Freiburg - Bad Krozingen

jan-steffen.pooth@universitaets-herzzentrum.de076127088888

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026