Influence of circadian rhythm on endogenous oxidative stress

Influence of circadian rhythm on endogenous oxidative stress - ZIROX

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00021046

Enrollment

Registered

2021-12-28

Start date

2022-01-17

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oxidative stress in surgical patients

Interventions

Group 1: Within this study, venous blood samples will be collected from inpatients on the day wards of the Clinic for Cardiovascular Surgery with an inserted indwelling venous catheter at defined time

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Treatment on a day ward at Freiburg University Hospital, inserted intravenous catheter, expected duration of inpatient treatment >72 hours

Exclusion criteria

Exclusion criteria: Non-consenting patients, minors, emergency patients, known hematologic or oncologic disease, presence of immunosuppression, patients with permanent mobility impairment (bedridden), body mass index less than 20 kg/m2.

Design outcomes

Primary

Measure	Time frame
Serum free radical concentration	—

Secondary

Measure	Time frame
Total protein concentration, pH, sleep duration, sleep quality, serum melatonin concentration	—

Countries

Germany

Contacts

Public ContactJan-Steffen Pooth

Universitäts-Herzzentrum Freiburg - Bad Krozingen

jan-steffen.pooth@universitaets-herzzentrum.de076127088888

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026