Neonatal Microbiota

Neonatal Microbiota - NeoMik

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00021034

Enrollment

100

Registered

2020-03-20

Start date

2016-01-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

P07 P77

Interventions

Group 1: Observational study: preterm neonates born < 32 week gestation, oral administration of probiotics consistent with clinical guidline, weekly collection of stool samples Group 2: preterm neonat

Eligibility

Sex/Gender

All

Age

3 Days to 3 Days

Inclusion criteria

Inclusion criteria: extreme preterm birth 31 week gestation)

Exclusion criteria

Exclusion criteria: inherited malformation of the gastrointestinal tract (gastrochisis, omphalocele, duodenal atresia)

Design outcomes

Primary

Measure	Time frame
Comparative analysis of the establishment of the enteric microbiota after birth (16S rDNA amplicon sequencing, analysis of richness, microbial composition, presence/absence of pathobionts, persistence of probiotic bacteria)	—

Secondary

Measure	Time frame
Necrotizing enterocolitis (NEC)	—

Countries

Germany

Contacts

Public ContactMathias Hornef

Institut für Medizinische Mikrobiologie Universitätsklinikum der RWTH Aachen

mhornef@ukaachen.de0241 80 89510

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026